Use of two methods to elute anti-IgG and anti-(IgG + C3d) type autoantibody from sensitized erythrocytes

Glycation of Human IgG Induces Structural Alterations Leading to Changes in its Interaction with Anti-IgG

Background: Glycation of proteins is a non-enzymatic spontaneous process that occurs in diabetes mellitus and aging, altering the structure and function of proteins. IgG undergoes glycation leading to changes in its reactivity to antigen and fixation of complement.   Objective: This study aimed at revealing the effect of glycation on the interaction of IgG with anti-IgG using electroimmunoassay...

The ingestion of IgG-sensitized erythrocytes by abnormal neutrophils.

Complement-independent clearance of IgG-sensitized erythrocytes: inhibition by cortisone.

ARE IgG-ANTI-FAB2ɤ AND IgG-ANTI-HINGE ANTIBODIES ACTIVE CONSTITUENTS OF INTRAVENOUS IMMUNOGLOBULIN?

Our aim was to find out if immunoglobulins for intravenous use (IVIG) contain IgG-anti-F(ab')2γ (AFab2) and IgG-antiHinge (AH) antibodies (Ab.) and to discuss how AFab2, in particular AH could contribute to immunomodulatory effect of IVIGs. We measured IgG, AFab2 and AH in five IVIG products approved for therapeutic use. IVIG showed higher AFab2 and AH concentration than sera of randomized heal...

Seroprevalence of anti-SARS-CoV-2 IgG antibody in healthcare workers: A report from Rafsanjan, Iran

Background: Healthcare workers (HCWs) have a high risk of SARS-CoV-2 infection. Seroprevalence studies can provide related data on HCWs who have a history of infections. According to numerous seroepidemiological reports of COVID-19 in different groups and the lack of seroepidemiological reports of COVID-19 in HCWs in Rafsanjan, the aim of this study was to determine the SARS-CoV-2 seroprevalenc...